SCHEMBL7058637

SCHEMBL7058637

CS(=O)(=O)NC(NS(C)(=O)=O)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
TSHR P16473 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
EP300 Q09472 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
POLB P06746 2/20 0.39
ACHE P22303 2/20 0.38
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
KEAP1 Q14145 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PGAM1 P18669 1/20 0.34
CYP3A4 P08684 2/20 0.34
MAPKAPK2 P49137 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27880591 0.76 GABRA1 (0.75) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL466037 0.73 GABRA1 (0.56) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL5794245 0.72 GABRA1 (0.50) GABRA1GABRB2TSHRL3MBTL1POLB
Catechol SCHEMBL11778548 0.71 SMN1; SMN2 (0.59) GABRA1GABRB2TSHRL3MBTL1EP300
SCHEMBL25435654 0.68 GABRA1 (0.56) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL27373607 0.68 GABRA1 (0.56) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL19469326 0.67 GABRA1 (0.48) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL6111717 0.65 EP300 (0.61) TSHRL3MBTL1EP300KAT2BKAT8
SCHEMBL4126186 0.65 GABRA1 (0.46) GABRA1GABRB2TSHRL3MBTL1POLB
SCHEMBL51565 0.65 GABRA1 (0.71) GABRA1GABRB2TSHRL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425328-A1 FAST-SETTING 1K-POLYURETHANE GLUE Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-09 EP disclosed
WO-2003016368-A1 FAST-SETTING 1K-POLYURETHANE GLUE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-02-27 WO disclosed
WO-2002009863-A2 MICROCAPSULE, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF IN ADHESIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO disclosed
WO-1999048942-A9 POLYURETHANE AND PREPARATION CONTAINING POLYURETHANE HENKEL KGAA (DE) 2001-03-22 WO disclosed