SCHEMBL466037

SCHEMBL466037

CNC(NC)c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.56
GABRB2 P47870 2/20 0.56
TSHR P16473 6/20 0.50
POLB P06746 2/20 0.44
CA2 P00918 3/20 0.41
LMNA P02545 3/20 0.41
CYP3A4 P08684 3/20 0.41
HPGD P15428 2/20 0.41
BLM P54132 2/20 0.41
HIF1A Q16665 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 2/20 0.41
NFKB1 P19838 2/20 0.41
THPO P40225 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
CA12 O43570 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10154250 0.79 GABRA1 (0.60) GABRA1GABRB2TSHRPOLBCA2
Bromide SCHEMBL15398507 0.77 GABRA1 (0.58) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL9402254 0.74 GABRA1 (0.48) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL9290334 0.73 GABRA1 (0.65) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL7058637 0.73 GABRA1 (0.47) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL12601482 0.73 GABRA1 (0.47) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL11626584 0.73 TSHR (0.52) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL51565 0.72 GABRA1 (0.71) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL11597764 0.72 GABRA1 (0.71) GABRA1GABRB2TSHRPOLBCA2
SCHEMBL43297 0.72 GABRA1 (1.00) GABRA1GABRB2TSHRPOLBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268757-B1 ADHESIVE MERCK PATENT GMBH (DE) 2012-01-18 EP disclosed
EP-1303569-B2 BINDING AGENTS AND BINDING AGENT COMPOSITIONS CONTAINING ALKOXY SILYL GROUPS, METHOD FOR THE PRODUCTION AND USE THEREOF HENKEL AG & CO KGAA (DE) 2011-07-27 EP disclosed
EP-1490418-B2 NEUTRAL-COLOURED 1K POLYURETHANE ADHESIVE HENKEL AG & CO KGAA (DE) 2011-06-29 EP disclosed
US-20110054074-A1 ADHESIVE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 2011-03-03 US disclosed
EP-2268757-A1 ADHESIVE Merck Patent GmbH (DE) 2011-01-05 EP disclosed
EP-1668090-B1 COHESION-REDUCED BINDER PRODUCTION AND USE THEREOF IN DETACHABLE ASSEMBLY ADHESIVES HENKEL AG & CO KGAA (DE) 2010-09-08 EP disclosed
WO-2009129923-A1 ADHESIVE MERCK PATENT GMBH (DE) 2009-10-29 WO disclosed
EP-0839832-B1 Use of a hydrophilic polyurethane in aqueous systems HENKEL AG & CO KGAA (DE) 2009-06-17 EP disclosed
EP-1425328-B1 FAST-SETTING 1K-POLYURETHANE GLUE HENKEL AG & CO KGAA (DE) 2008-11-26 EP disclosed
EP-1625189-B1 WATER-SOLUBLE HOT-MELT ADHESIVE HENKEL AG & CO KGAA (DE) 2008-11-19 EP disclosed
EP-0815152-B1 PROTECTIVE COLLOIDS COGNIS DEUTSCHLAND GMBH (DE) 1999-11-10 EP disclosed
EP-0933412-A1 Water-resistant adhesive based on a vinyl acetate emulsion polymer containing a nonionic polyurethane National Starch and Chemical Investment Holding Corporation (US) 1999-08-04 EP disclosed
WO-1999015573-A1 POLYURETHANE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-04-01 WO disclosed
EP-0674675-B1 HYDROPHILIC POLYURETHANES HENKEL KGAA (DE) 1998-07-29 EP disclosed
EP-0839832-A1 Use of a hydrophilic polyurethane in aqueous systems Henkel Kommanditgesellschaft auf Aktien (DE) 1998-05-06 EP disclosed
EP-0838511-A1 Use of an hydrophilic polyurethane Henkel Kommanditgesellschaft auf Aktien (DE) 1998-04-29 EP disclosed
EP-0828801-A1 BONDING PROCESS Henkel Kommanditgesellschaft auf Aktien (DE) 1998-03-18 EP disclosed
EP-0815152-A1 PROTECTIVE COLLOIDS Henkel Kommanditgesellschaft auf Aktien (DE) 1998-01-07 EP disclosed
WO-1996037566-A1 BONDING PROCESS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-11-28 WO disclosed
WO-1996028489-A1 PROTECTIVE COLLOIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-09-19 WO disclosed