Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.63 |
| ▸ | CCR3 | P51677 | 6/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053083 | 0.89 | CCR3 (0.63) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| SCHEMBL7057153 | 0.85 | CCR3 (0.54) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| Hydrochloric Acid SCHEMBL7059854 | 0.82 | CCR3 (0.51) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| SCHEMBL7057687 | 0.82 | CCR3 (0.50) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| SCHEMBL7057298 | 0.81 | DRD2 (0.57) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| SCHEMBL7056585 | 0.80 | CCR3 (0.67) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| Hydrochloric Acid SCHEMBL7052602 | 0.77 | DRD4 (0.53) | SLC6A2SLC6A4CCR3TMEM97DRD2 | |
| SCHEMBL18507049 | 0.75 | L3MBTL3 (0.58) | SLC6A2SLC6A4DRD2DRD3CHRM4 | |
| SCHEMBL7119593 | 0.73 | CCR3 (0.55) | CCR3DRD2DRD3 | |
| SCHEMBL3117938 | 0.73 | SLC6A2 (0.49) | SLC6A2SLC6A4CCR3TMEM97DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |