Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921595 | 0.94 | BCL2L1 (0.48) | TSHRTP53TPMTSRD5A2CA1 | |
| SCHEMBL18190945 | 0.89 | RARA (0.51) | TSHRTP53SRD5A2ALDH1A1NPC1 | |
| SCHEMBL18190944 | 0.89 | RARA (0.51) | TSHRTP53SRD5A2ALDH1A1NPC1 | |
| SCHEMBL16652340 | 0.85 | RARB (0.49) | TP53ALDH1A1SMN1; SMN2ALOX15 | |
| Isophthalic Acid SCHEMBL6752087 | 0.84 | KMO (0.49) | CA1CA2CA12CA6CA9 | |
| Benzene SCHEMBL27857640 | 0.81 | AKR1C1 (0.44) | TSHRALDH1A1SMN1; SMN2AKR1C1 | |
| SCHEMBL517831 | 0.81 | CYP2C19 (0.46) | TSHRALDH1A1SMN1; SMN2AKR1C1 | |
| SCHEMBL5509416 | 0.81 | CYP2C19 (0.46) | TSHRALDH1A1SMN1; SMN2AKR1C1 | |
| SCHEMBL518477 | 0.81 | CYP2C19 (0.46) | TSHRALDH1A1SMN1; SMN2AKR1C1 | |
| SCHEMBL20679048 | 0.81 | CYP2C19 (0.46) | TSHRALDH1A1SMN1; SMN2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161497-B1 | POLYAMIDE/EMULSION POLYMER BLENDS | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | EP | claimed |
| CN-109982844-A | Composite component | 宇部兴产株式会社 | 2019-07-05 | — | — | CN | disclosed |
| CN-105719724-B | Heat-curing type conductive paste | 株式会社则武 | 2019-05-03 | — | — | CN | disclosed |
| US-20160377780-A1 | OPTICAL REFLECTION FILM | Konica Minolta, Inc. (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20150177433-A1 | INFRARED SHIELDING FILM | Konica Minolta, Inc. (JP) | 2015-06-25 | — | — | US | disclosed |
| EP-2873993-A1 | INFRARED-SHIELDING FILM | Konica Minolta, Inc. (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-6303257-B1 | FOR DEVELOPING AN ELECTROSTATIC LATENT IMAGE FORMED BY ELECTROPHOTOGRAPHY AND THE LIKE | RICOH COMPANY LIMITED (JP) | 2001-10-16 | — | — | US | disclosed |