⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856591 | 0.70 | — | — | |
| SCHEMBL8346090 | 0.68 | — | — | |
| SCHEMBL2462235 | 0.67 | — | — | |
| SCHEMBL2462233 | 0.67 | — | — | |
| SCHEMBL439352 | 0.67 | — | — | |
| SCHEMBL5420428 | 0.67 | — | — | |
| SCHEMBL2309 | 0.67 | — | — | |
| SCHEMBL1364768 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL3128037 | 0.67 | — | — | |
| SCHEMBL210425 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459260-B | 1-pyrazolo[4,3-c]isoquinoline derivatives, preparation thereof and therapeutic use thereof | SANOFI AVENTIS | 2015-06-10 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104230974-A | Pyrrole-pyridine compound and preparation method thereof | TIANJIN SPHINX DRUG RES AND DEV CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-102686551-B | Process for producing cycloalkanedicarboxylic acid monoester | SUMITOMO CHEMICAL CO | 2014-11-12 | — | — | CN | claimed |
| CN-104109235-A | Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter | XIAMEN SINOPEG BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| CN-103403010-A | inhibitors of POLO-like kinases | ELAN PHARM INC | 2013-11-20 | — | — | CN | claimed |
| CN-102227424-B | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMA | 2013-08-14 | — | — | CN | claimed |
| CN-102834387-A | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | BAYER CROPSCIENCE AG | 2012-12-19 | — | — | CN | claimed |
| CN-102762568-A | Pteridinones as inhibitors of polo - like kinase | ELAN PHARM INC | 2012-10-31 | — | — | CN | claimed |
| CN-102459281-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | claimed |
| CN-102227424-A | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMA | 2011-10-26 | — | — | CN | claimed |
| CN-102227430-A | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMA | 2011-10-26 | — | — | CN | claimed |
| CN-101675042-A | Novel 2-heteroaryl substituted benzothiophenes and benzofurans 709 | ASTRAZENECA AB | 2010-03-17 | — | — | CN | claimed |
| CN-101641354-A | Novel heteroaryl substituted imidazo [1,2 -a] pyridine derivatives | ASTRAZENECA AB SE | 2010-02-03 | — | — | CN | claimed |
| CN-101636395-A | Novel 2-heteroaryl substituted indoles 695 | ASTRAZENECA AB | 2010-01-27 | — | — | CN | claimed |
| CN-101506201-A | Novel heteroaryl substituted benzoxazoles | ASTRAZENECA AB (SE) | 2009-08-12 | — | — | CN | claimed |
| CN-101410393-A | Novel heteroaryl substituted benzothiazoles | ASTRAZENECA AB (SE) | 2009-04-15 | — | — | CN | claimed |
| CN-1093128-C | Process for preparing eprosartan | SMITHKLINE BEECHAM CORP (US) | 2002-10-23 | — | — | CN | claimed |
| CN-1247538-A | Process for preparing eprosartan | SMITHKLINE BEECHAM CORP (US) | 2000-03-15 | — | — | CN | claimed |