Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059454 | 0.83 | MEN1 (0.38) | KDM4EMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL9366943 | 0.83 | MAPT (0.39) | KDM4EMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL9522187 | 0.81 | KDM4E (0.44) | KDM4EMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL8057087 | 0.80 | MAPT (0.38) | KDM4EMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL9381252 | 0.79 | MAPT (0.34) | GAAKDM4EMAPTNPC1TP53 | |
| SCHEMBL9521846 | 0.78 | MAPT (0.37) | MAPTNPC1TP53SMN1; SMN2RAB9A | |
| SCHEMBL9521705 | 0.78 | PTGS2 (0.41) | GAAKDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7603698 | 0.78 | MAPT (0.39) | KDM4EMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL9363731 | 0.77 | MAPT (0.32) | MAPT | |
| SCHEMBL7919531 | 0.76 | MAPT (0.33) | MAPTNPC1TP53SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003033712-A1 | CHEMICALLY INDUCIBLE PROMOTERS FROM BARLEY AND USE THEREOF | BASF PLANT SCIENCE GMBH (DE) | 2003-04-24 | — | — | WO | disclosed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |