Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366943 | 0.84 | MAPT (0.39) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9522187 | 0.82 | KDM4E (0.44) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL8057087 | 0.81 | MAPT (0.38) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7059454 | 0.81 | MEN1 (0.38) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7059356 | 0.78 | GAA (0.35) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7919531 | 0.78 | MAPT (0.33) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL8051713 | 0.77 | MAOB (0.40) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9521846 | 0.77 | MAPT (0.37) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6969847 | 0.75 | NQO2 (0.47) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9363731 | 0.75 | MAPT (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968179-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-0968178-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| US-6277849-B1 | FOR PROTECTION OF PLANTS AGAINST PHYTOPATHOGENIC MICROORGANISM INFESTATION | SYNGENTA CROP PROTECTION, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6194463-B1 | SUCH AS ALPHA-(ETHYLSULFONYLAMINO)-CYCLOHEXANEACETIC ACID N-(2-(4-HYDROXY-3-METHOXYPHENYL)-ETHYL)-AMIDE; USE SUCH AS FOR CONTROLLING FUNGAL DISEASES IN CROPS | NOVARTIS CROP PROTECTION, INC. | 2001-02-27 | — | — | US | disclosed |