Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503331 | 0.87 | CYP19A1 (0.84) | CYP19A1ALOX15ALOX12KCNH2TRPV1 | |
| SCHEMBL13267887 | 0.85 | CYP19A1 (1.00) | CYP19A1ALOX15ALOX12 | |
| SCHEMBL13311871 | 0.84 | CYP19A1 (1.00) | CYP19A1 | |
| Isoflavanone SCHEMBL72983 | 0.83 | CYP19A1 (1.00) | CYP19A1 | |
| Isoflavanone SCHEMBL15883785 | 0.83 | CYP19A1 (1.00) | CYP19A1 | |
| Isoflavanone SCHEMBL30593548 | 0.83 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL29559241 | 0.82 | ALOX12 (0.74) | CYP19A1ALOX15ALOX12KCNH2TRPV1 | |
| SCHEMBL2069507 | 0.82 | ALOX12 (0.74) | CYP19A1ALOX15ALOX12KCNH2TRPV1 | |
| SCHEMBL4806201 | 0.81 | CYP19A1 (0.77) | CYP19A1ALOX12 | |
| SCHEMBL13382254 | 0.81 | CYP19A1 (0.77) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8124390-B2 | Aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100285502-A1 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. | 2010-11-11 | — | — | US | disclosed |
| US-7544498-B2 | Aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2009-06-09 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| US-7462478-B2 | isolated from licorice; catalyzes a dehydration reaction of 2-hydroxy hisoflavanone | NIHON UNIVERSITY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20080274478-A1 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TOL, LTD. | 2008-11-06 | — | — | US | disclosed |
| US-7361483-B2 | Aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-04-22 | — | — | US | disclosed |
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20070050865-A1 | Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same | NIHON UNIVERSITY (JP) | 2007-03-01 | — | — | US | disclosed |
| US-20060183211-A1 | Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. | 2006-08-17 | — | — | US | disclosed |
| WO-2006081537-A2 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2006-08-03 | — | — | WO | disclosed |