SCHEMBL7059488

SCHEMBL7059488

CCOC(=O)CCC(C)[C]=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
KMT2A Q03164 2/20 0.45
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.44
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ALDH1A1 P00352 5/20 0.40
TRPA1 O75762 1/20 0.40
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PTGS2 P35354 1/20 0.36
PDE4D Q08499 1/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19233796 0.82 L3MBTL1 (0.46) L3MBTL1KMT2APOLBCYP1A2GAA
SCHEMBL9771169 0.79 MGAM (0.46) L3MBTL1CYP1A2GAAMGAMSI
SCHEMBL7064658 0.79 TSHR (0.50) L3MBTL1KMT2AGAAMGAMSI
SCHEMBL103981 0.79 L3MBTL1 (0.53) L3MBTL1KMT2APOLBCYP1A2GAA
SCHEMBL29175194 0.77 L3MBTL1 (0.52) L3MBTL1KMT2APOLBCYP1A2GAA
Hydrochloric Acid SCHEMBL29184682 0.77 L3MBTL1 (0.52) L3MBTL1KMT2APOLBCYP1A2GAA
Hydrochloric Acid SCHEMBL30807122 0.77 L3MBTL1 (0.52) L3MBTL1KMT2APOLBCYP1A2GAA
SCHEMBL985537 0.77 L3MBTL1 (0.52) L3MBTL1KMT2APOLBCYP1A2GAA
SCHEMBL12510627 0.77 GABRP (0.54) L3MBTL1KMT2APOLBCYP1A2GAA
SCHEMBL8410329 0.75 L3MBTL1 (0.50) L3MBTL1KMT2APOLBCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216258-A1 Condensed heterocylic compounds and herbicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LIMITED 2003-11-20 US disclosed
US-6586368-B1 Benzofuran derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
EP-1112268-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-07-04 EP disclosed
WO-2000015633-A1 CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-23 WO disclosed
US-5008290-A Anticoagulant DR. KARL THOMAE GMBH (DE) 1991-04-16 US disclosed
US-4929754-A CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS DR. KARL THOMAE GMBH (DE) 1990-05-29 US disclosed
US-4870076-A ANTICOAGULANTS KARL THOMAE GMBH (DE) 1989-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216258-A1 Condensed heterocylic compounds and herbicides containing them as active ingredients CBR3, CBR1, HAAO L3MBTL1 1199/4885KMT2A 565/4885POLB 2301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.