⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657283 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL11629152 | 0.70 | KDM1A (0.33) | — | |
| SCHEMBL28341268 | 0.70 | KDM4E (0.38) | — | |
| SCHEMBL13425231 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL11696235 | 0.67 | POLB (0.30) | — | |
| SCHEMBL21385202 | 0.67 | POLB (0.30) | — | |
| SCHEMBL4369386 | 0.66 | HIF1A (0.33) | — | |
| SCHEMBL30320303 | 0.66 | HIF1A (0.33) | — | |
| SCHEMBL10581338 | 0.66 | KDM4E (0.34) | — | |
| SCHEMBL30897428 | 0.66 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989122-B1 | Process for the preparation of imidazolidine-2,4-diones | DEGUSSA (DE) | 2003-05-21 | — | — | EP | disclosed |
| US-6235910-B1 | BY REACTING AN ALDEHYDE COMPOUND WITH A UREA COMPOUND IN THE PRESENCE OF CARBON MONOXIDE AND A CATALYTICALLY ACTIVE METAL COMPOUND. | DEGUSSA-HULS AG (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0989122-A1 | Process for the preparation of imidazolidine-2,4-diones | Degussa-Hüls Aktiengesellschaft (DE) | 2000-03-29 | — | — | EP | disclosed |