Thiram

Thiram

SCHEMBL7059869

CN(C)C(=O)S.CN(C)C(=S)SSC(=S)N(C)C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
MGLL Q99685 5/20 0.68
LMNA P02545 4/20 0.68
ALDH2 P05091 4/20 0.68
HTT P42858 3/20 0.68
MAPT P10636 3/20 0.68
KMT2A Q03164 3/20 0.68
FAAH O00519 3/20 0.68
TP53 P04637 2/20 0.68
HSP90AA1 P07900 2/20 0.68
CYP3A4 P08684 2/20 0.68
FBP1 P09467 2/20 0.68
PKM P14618 2/20 0.68
HPGD P15428 2/20 0.68
ALOX15 P16050 2/20 0.68
ALOX12 P18054 2/20 0.68
LOX P28300 2/20 0.68
LOXL3 P58215 2/20 0.68
NPSR1 Q6W5P4 2/20 0.68
LOXL4 Q96JB6 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiram SCHEMBL7271636 0.87 ALDH1A1 (0.65) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL11703083 0.83 ALDH1A1 (0.77) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL23248449 0.83 MGLL (0.87) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL28210418 0.83 MGLL (0.87) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL21144 0.83 ALDH1A1 (1.00) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL1216571 0.83 ALDH1A1 (1.00) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL28105703 0.81 ALDH1A1 (0.72) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL11574239 0.81 ALDH1A1 (0.72) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL28168393 0.81 ALDH1A1 (0.72) ALDH1A1MGLLLMNAALDH2HTT
Thiram SCHEMBL28131396 0.80 ALDH1A1 (0.81) ALDH1A1MGLLLMNAALDH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753003-B1 ANHYDROUS OIL PHASE, POLYHYDROXYSTEARIC ACID, ANIONIC SURFACTANT; STORAGE STABILITY; LOW VISCOSITY; METIRAM BASF AKTIENGESELLSCHAFT (DE) 2004-06-22 US disclosed
EP-1180935-B1 DITHIOCARBAMATE LIQUID FORMULATIONS BASF AG (DE) 2003-10-08 EP disclosed