SCHEMBL7059927

SCHEMBL7059927

CCCN(CCC)C(=O)c1ccccc1N

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.76
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 5/20 0.50
HPGD P15428 1/20 0.49
POLB P06746 1/20 0.46
CFTR P13569 1/20 0.46
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43
MLYCD O95822 1/20 0.42
LMNA P02545 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
TSHR P16473 1/20 0.41
P2RX1 P51575 1/20 0.41
P2RX3 P56373 1/20 0.41
P2RX4 Q99571 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6372806 0.93 TP53 (0.66) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL9036669 0.90 TP53 (0.61) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL6367079 0.86 TP53 (0.57) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL6371982 0.85 KDM4E (0.64) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL6371222 0.84 TP53 (0.53) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL7123985 0.82 TP53 (0.82) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL11146062 0.81 KDM4E (0.55) TP53KDM4EALDH1A1HSD17B10HPGD
SCHEMBL10330501 0.80 TP53 (0.79) TP53KDM4EEGFRERBB2MAPT
SCHEMBL14392032 0.80 KDM4E (0.57) TP53KDM4EALDH1A1HSD17B10MAPT
SCHEMBL3856120 0.79 TP53 (0.76) TP53EGFRERBB2MAPTMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11116834-A None JP disclosed
EP-0887793-B1 Optical recording elements containing metallized carbamoylazo dyes EASTMAN KODAK CO (US) 2003-05-21 EP disclosed
EP-0887792-B1 Optical recording element containing mixtures of metallized carbamoylazo and cyanine dyes EASTMAN KODAK CO (US) 2003-05-21 EP disclosed
EP-0887385-B1 Novel metallized carbamoylazo dyes EASTMAN KODAK CO (US) 2002-03-06 EP disclosed
JP-H11116834-A METAL-CONTAINING CARBAMOYLAZO DYE EASTMAN KODAK CO 1999-04-27 JP disclosed
US-5879774-A DIGITAL VERSATILE DISK (DVD) OPTICAL RECORDING ELEMENT MADE WITH A CURED CYANOACRYLATE ADHESIVE AND CONTAINING AN UNSATURATED POLYMERIC PROTECTIVE LAYER HAVING A MONOMER CONTAINING AMINE GROUPS AS A CURE ACCELERATOR; NONWARPING EASTMAN KODAK COMPANY (US) 1999-03-09 US disclosed
EP-0887792-A1 Optical recording element containing mixtures of metallized carbamoylazo and cyanine dyes EASTMAN KODAK COMPANY (US) 1998-12-30 EP disclosed
EP-0887793-A1 Optical recording elements containing metallized carbamoylazo dyes EASTMAN KODAK COMPANY (US) 1998-12-30 EP disclosed
EP-0887385-A1 Novel metallized carbamoylazo dyes EASTMAN KODAK COMPANY (US) 1998-12-30 EP disclosed
US-5821029-A MULTILAYER OPTICAL RECORDING ELEMENT WITH REFLECTING LAYER AND METALLIZED CARBAMOYLAZO DYE WITH CYANINE DYE EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5821346-A AZO GROUP LINKS A SUBSTITUTED 3-HYDROXYPYRIDINE NUCLEUS TO A PHENYL NUCLEUS; USEFUL IN OPTICAL RECORDING ELEMENTS EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5786124-A DIGITAL VERSATILE DISC EASTMAN KODAK COMPANY (US) 1998-07-28 US disclosed