SCHEMBL6371982

SCHEMBL6371982

CCN(CC)C(=O)c1ccccc1N

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
HSD17B10 Q99714 5/20 0.56
TP53 P04637 1/20 0.53
ALDH1A1 P00352 7/20 0.53
KEAP1 Q14145 1/20 0.53
HPGD P15428 3/20 0.51
TSHR P16473 3/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 4/20 0.49
CFTR P13569 1/20 0.48
GAA P10253 1/20 0.46
POLB P06746 1/20 0.45
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6372806 0.90 TP53 (0.66) KDM4EHSD17B10TP53ALDH1A1KEAP1
SCHEMBL17786077 0.87 KDM4E (0.54) KDM4EHSD17B10TP53ALDH1A1KEAP1
SCHEMBL610480 0.86 TP53 (0.69) TP53ALDH1A1KEAP1HPGDTSHR
SCHEMBL29822323 0.86 TP53 (0.69) TP53ALDH1A1KEAP1HPGDTSHR
SCHEMBL7059927 0.85 TP53 (0.76) KDM4EHSD17B10TP53ALDH1A1HPGD
SCHEMBL13256604 0.84 KDM4E (0.51) KDM4EHSD17B10TP53ALDH1A1KEAP1
SCHEMBL1706516 0.84 MMP2 (0.55) KDM4EHSD17B10TP53ALDH1A1KEAP1
SCHEMBL23891117 0.83 KDM4E (0.53) KDM4EHSD17B10TP53ALDH1A1HPGD
SCHEMBL3628079 0.83 KDM4E (0.53) KDM4EHSD17B10TP53ALDH1A1KEAP1
SCHEMBL29478348 0.82 TSHR (0.62) KDM4EHSD17B10TP53ALDH1A1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976034-B1 Coloring compound, yellow toner, ink, thermal transfer recording sheet, and color filter resist composition CANON KABUSHIKI KAISHA (JP) 2018-05-22 US disclosed
US-9976034-B1 Coloring compound, yellow toner, ink, thermal transfer recording sheet, and color filter resist composition CANON KABUSHIKI KAISHA (JP) 2018-05-22 US disclosed
US-20180118944-A1 COLORING COMPOUND, YELLOW TONER, INK, THERMAL TRANSFER RECORDING SHEET, AND COLOR FILTER RESIST COMPOSITION CANON KABUSHIKI KAISHA (JP) 2018-05-03 US disclosed
US-20180118944-A1 COLORING COMPOUND, YELLOW TONER, INK, THERMAL TRANSFER RECORDING SHEET, AND COLOR FILTER RESIST COMPOSITION CANON KABUSHIKI KAISHA (JP) 2018-05-03 US disclosed
US-6884801-B1 Imidazoline derivatives as alpha-1A adrenoceptor ligands SMITHKLINE BEECHAM CORPORATION (US) 2005-04-26 US disclosed
EP-1175406-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2002-01-30 EP disclosed
WO-2000066563-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2000-11-09 WO disclosed
EP-0133310-B1 IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1988-09-14 EP disclosed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
US-4608079-A Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1986-08-26 US disclosed
EP-0133310-A1 Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1985-02-20 EP disclosed