Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802362 | 0.93 | HTR2A (0.63) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL16036062 | 0.89 | KMT2A (0.46) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| Ammonia Solution, Strong SCHEMBL6000438 | 0.85 | CYP17A1 (0.56) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL7979678 | 0.80 | HTR2A (0.48) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL4731046 | 0.79 | HDAC8 (0.50) | HTR2ASLC6A2SLC6A3CHRM2CHRM1 | |
| Ammonia Solution, Strong SCHEMBL5999471 | 0.78 | SLC6A4 (0.44) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL12506256 | 0.78 | HTR2A (0.56) | HTR2AHRH1LMNATAAR1 | |
| SCHEMBL2600188 | 0.77 | ALDH1A1 (0.44) | HTR2ACYP2A6ALDH1A1CYP2C9HPGD | |
| SCHEMBL10610871 | 0.77 | CYP1A2 (0.43) | HTR2ACYP2D6CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL28344445 | 0.77 | ALDH1A1 (0.44) | HTR2ACYP2A6ALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646096-B2 | Manipulation of a control scheme for operating, controlling, monitoring and diagnosing various parameters and processes of polycarbonate batch-wise reactions, resulting in accurate determination of batch completion for reactions | GENERAL ELECTRIC COMPANY | 2003-11-11 | — | — | US | disclosed |
| US-20020111455-A1 | Method for controlling the manufacture of polycarbonate and the polycarbonate formed thereby | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2002-08-15 | — | — | US | disclosed |
| WO-2002057337-A2 | METHOD FOR CONTROLLING THE MANUFACTURE OF POLYCARBONATE AND THE POLYCARBONATE FORMED THEREBY | GENERAL ELECTRIC COMPANY (US) | 2002-07-25 | — | — | WO | disclosed |