SCHEMBL70604

SCHEMBL70604

CCOC(=O)c1ccc2c(c1)[nH]c1ccc(C(=O)OCC)cc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.81
KDM4E B2RXH2 7/20 0.81
MAPT P10636 6/20 0.81
MEN1 O00255 3/20 0.81
KMT2A Q03164 3/20 0.81
RAB9A P51151 3/20 0.81
SMN1; SMN2 Q16637 3/20 0.81
HCRTR1 O43613 2/20 0.81
HSD17B10 Q99714 5/20 0.66
MAPK1 P28482 3/20 0.66
HPGD P15428 3/20 0.66
POLB P06746 2/20 0.66
NPC1 O15118 2/20 0.60
TUBB4A P04350 1/20 0.57
TUBB P07437 1/20 0.57
TUBA3C P0DPH7 1/20 0.57
TUBA1B P68363 1/20 0.57
TUBA4A P68366 1/20 0.57
TUBB4B P68371 1/20 0.57
TUBB3 Q13509 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6007665 0.94 ALDH1A1 (0.70) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL68639 0.94 KDM4E (0.85) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL15995185 0.90 KDM4E (0.71) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL6009670 0.90 KDM4E (0.84) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL4726935 0.90 KDM4E (1.00) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL4728034 0.88 KDM4E (0.76) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL6009615 0.88 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL7979591 0.85 KDM4E (0.72) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL541732 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL10644857 0.84 KDM4E (0.70) ALDH1A1KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885KDM4E 717/4885MAPT 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.