Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68639 | 0.94 | KDM4E (0.85) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL70604 | 0.88 | ALDH1A1 (0.81) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4726935 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12642105 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7979591 | 0.85 | KDM4E (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10375171 | 0.84 | GABRA1 (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL541732 | 0.84 | ALDH1A1 (0.71) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6983821 | 0.84 | HCRTR1 (0.76) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3187981 | 0.82 | HCRTR1 (0.70) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15995185 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |