Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.49 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060721 | 1.00 | TNFRSF1A (0.49) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL6917803 | 0.88 | TNFRSF1A (0.48) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL6917804 | 0.88 | TNFRSF1A (0.48) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL7065034 | 0.88 | TNFRSF1A (0.50) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL6916935 | 0.88 | TNFRSF1A (0.50) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL6916852 | 0.88 | GABBR2 (0.55) | TNFRSF1AGABBR2GABBR1HTTCYP1A2 | |
| SCHEMBL7062330 | 0.87 | TNFRSF1A (0.45) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL7062332 | 0.87 | TNFRSF1A (0.45) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL7064909 | 0.87 | TNFRSF1A (0.49) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD | |
| SCHEMBL7064912 | 0.87 | TNFRSF1A (0.49) | TNFRSF1AGABBR2GABBR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |