Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703098 | 0.91 | ALDH1A1 (0.39) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL10704257 | 0.89 | MAPT (0.38) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL10706838 | 0.89 | MAPT (0.38) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL30966777 | 0.86 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL13990194 | 0.86 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL10705851 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL9750141 | 0.77 | PDK2 (0.44) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL16491626 | 0.75 | ESR2 (0.55) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL61554 | 0.75 | MAPT (0.42) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL11865676 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339800-A1 | SQUARAINE BASED DYES AND PROCESS FOR PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2003-09-03 | — | — | EP | disclosed |
| WO-2003035768-A1 | SQUARAINE BASED DYES AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | WO | disclosed |
| EP-0146301-B1 | PROCESS FOR SYNTHESIZING SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1988-07-13 | — | — | EP | disclosed |