Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594139 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL30966777 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL13990194 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL11964694 | 0.81 | ALDH1A1 (0.33) | MAPTALDH1A1TSHRHSD17B10APP | |
| SCHEMBL11964700 | 0.80 | CNR1 (0.36) | MAPTALDH1A1TSHRHSD17B10APP | |
| SCHEMBL7060856 | 0.75 | MAPT (0.44) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL13569256 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL172750 | 0.74 | TDP1 (0.52) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL9750141 | 0.73 | PDK2 (0.44) | MAPTALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL10667441 | 0.73 | ALDH1A1 (0.41) | MAPTALDH1A1TSHRHSD17B10ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MAPT 2743/4885ALDH1A1 1435/4885TSHR 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.