Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067151 | 0.92 | GAA (0.40) | GAACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7068101 | 0.91 | SLC6A2 (0.46) | GAAALDH1A1SMN1; SMN2MGLLSLC6A3 | |
| SCHEMBL7066363 | 0.91 | OPRM1 (0.44) | GAACHRM2ALDH1A1SMN1; SMN2OPRK1 | |
| SCHEMBL7060888 | 0.86 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2773433 | 0.86 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2772366 | 0.86 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2772125 | 0.86 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7064464 | 0.86 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7066810 | 0.84 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7064427 | 0.83 | HCAR2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |