SCHEMBL7062228

SCHEMBL7062228

c1ccc(-c2cnc(-c3ccccc3)n2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.50
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGDS O60760 2/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
PI4KA P42356 1/20 0.45
PI4K2B Q8TCG2 1/20 0.45
PI4K2A Q9BTU6 1/20 0.45
PI4KB Q9UBF8 1/20 0.45
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CHEK1 O14757 1/20 0.43
MAPT P10636 1/20 0.43
LIMK1 P53667 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3583887 0.92 AVPR1A (0.51) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL18674877 0.87 AVPR1A (0.44) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL11868284 0.86 ALDH1A1 (0.53) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL13197415 0.86 KIF11 (0.49) AVPR1AHPGDSMN1; SMN2MEN1KMT2A
SCHEMBL11868278 0.86 ALDH1A1 (0.53) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL11991172 0.84 AVPR1A (0.49) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL12306759 0.84 HPGD (0.46) AVPR1AHPGDSMN1; SMN2HPGDSKMT2A
SCHEMBL28087495 0.84 AKT1 (0.44) AVPR1AHPGDSMN1; SMN2MEN1KMT2A
SCHEMBL18999334 0.83 ALDH1A1 (0.41) AVPR1AHPGDSMN1; SMN2HPGDSMEN1
SCHEMBL24890358 0.82 AVPR1A (0.58) AVPR1AHPGDSMN1; SMN2HPGDSMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN disclosed
EP-0924281-B1 Organic light emitting diode with a terbium complex PHILIPS INTELLECTUAL PROPERTY (DE) 2003-05-21 EP disclosed