Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CCR1 | P32246 | 3/20 | 0.63 |
| ▸ | CCR5 | P51681 | 3/20 | 0.63 |
| ▸ | CCR8 | P51685 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581100 | 0.98 | KDM4E (0.67) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL244011 | 0.85 | CCR1 (0.46) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL18769070 | 0.82 | KDM4E (0.65) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL9526361 | 0.82 | KDM4E (0.55) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL2720906 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL7062285 | 0.81 | KCNH2 (0.61) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL313802 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL2720567 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL20863011 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2LMNACCR1CCR5 | |
| SCHEMBL2085837 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2LMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374195-A1 | Value Chain Return Process for Spent Polyurethanes by Hydrogenation | BASF SE (DE) | 2023-11-23 | — | — | US | disclosed |
| WO-2022136147-A1 | BISPIDINE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2022-06-30 | — | — | WO | disclosed |
| EP-4019051-A1 | BISPIDINE DERIVATIVES AND THE USE THEREOF | Helmholtz-Zentrum Dresden - Rossendorf e.V. (DE) | 2022-06-29 | — | — | EP | disclosed |
| WO-2018134847-A1 | IMMUNOSUPPRESSIVE AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-07-26 | — | — | WO | disclosed |
| US-20170107251-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-04-20 | — | — | US | disclosed |
| US-9564274-B2 | Metal complex dye, photoelectric conversion element, dye-sensitized solar cell, dye solution, and compound | FUJIFILM CORPORATION (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20150284417-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-10-08 | — | — | US | disclosed |
| US-9045381-B2 | Ruthenium complexes and their uses in processes for formation and/or hydrogenation of esters, amides and derivatives thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-06-02 | — | — | US | disclosed |
| US-20140290746-A1 | METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20130281664-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2013-10-24 | — | — | US | disclosed |
| US-8323621-B2 | site-directed delivery of contrast agent; brain or breast cancer; 1,4,7,10 tetraazacyclododecane having variable chelating ions, phosphoester chains, and light harvesting moieties for changing imaging methods; conjugated to high affinity PBR ligand PK11195; bound to a PVA or a PEG delivery vehicle | VANDERBILT UNIVERSITY (US) | 2012-12-04 | — | — | US | disclosed |
| US-8323621-B2 | site-directed delivery of contrast agent; brain or breast cancer; 1,4,7,10 tetraazacyclododecane having variable chelating ions, phosphoester chains, and light harvesting moieties for changing imaging methods; conjugated to high affinity PBR ligand PK11195; bound to a PVA or a PEG delivery vehicle | VANDERBILT UNIVERSITY (US) | 2012-12-04 | — | — | US | disclosed |
| US-20090318667-A1 | Peptoid compositions and methods of using the same | NEW YORK UNIVERSITY | 2009-12-24 | — | — | US | disclosed |
| WO-2009139922-A2 | PEPTOID COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20080241873-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | BORNHOP DARRYL J | 2008-10-02 | — | — | US | disclosed |
| US-20080241873-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | BORNHOP DARRYL J | 2008-10-02 | — | — | US | disclosed |
| US-20080241074-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | VANDERBILT UNIVERSITY | 2008-10-02 | — | — | US | disclosed |
| US-20080241074-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | VANDERBILT UNIVERSITY | 2008-10-02 | — | — | US | disclosed |
| US-7338651-B2 | Multi-use multimodal imaging chelates | TEXAS TECH UNIVERSITY SYSTEM (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338651-B2 | Multi-use multimodal imaging chelates | TEXAS TECH UNIVERSITY SYSTEM (US) | 2008-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107251-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | ADH1C, ADH5, ADH1A | KDM4E 3496/4885SMN1; SMN2 4864/4885LMNA 3705/4885 |
| US-20090318667-A1 | Peptoid compositions and methods of using the same | PEPD, NGLY1, ANPEP | KDM4E 4041/4885SMN1; SMN2 2812/4885LMNA 2533/4885 |
| US-20080241074-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | PCNA, CLTC, CLTB | KDM4E 1276/4885SMN1; SMN2 4260/4885LMNA 1635/4885 |
| US-20150284417-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | ADH1C, ADH5, ADH1A | KDM4E 3496/4885SMN1; SMN2 4864/4885LMNA 3705/4885 |
| US-20130281664-A1 | NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | ADH5, ADH1C, ADH1A | KDM4E 2909/4885SMN1; SMN2 4862/4885LMNA 3187/4885 |
| US-20080241873-A1 | MULTI-USE MULTIMODAL IMAGING CHELATES | PCNA, CLTC, CLTB | KDM4E 1276/4885SMN1; SMN2 4260/4885LMNA 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.