SCHEMBL7062408

SCHEMBL7062408

Cc1ccc(S(=O)(=O)ON(N=Cc2cccc(I)c2)C(=N)N)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
LMNA P02545 6/20 0.39
HPGD P15428 1/20 0.39
MAPT P10636 6/20 0.37
GAA P10253 2/20 0.37
G6PD P11413 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GFER P55789 1/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPK1 P28482 1/20 0.34
SCN2A Q99250 1/20 0.34
HTT P42858 2/20 0.34
SPHK2 Q9NRA0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915932 0.86 PTGS2 (0.47) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL915169 0.85 ALDH1A1 (0.53) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL7065388 0.81 ATM (0.38) ALDH1A1LMNAMAPTGAAGFER
SCHEMBL7062964 0.81 GFER (0.38) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL7062979 0.81 GFER (0.38) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL7065198 0.81 ATM (0.45) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL7065942 0.81 MAPT (0.44) ALDH1A1LMNAMAPTGAANPSR1
SCHEMBL7062403 0.80 CYP2D6 (0.40) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL7062405 0.80 CYP2D6 (0.40) ALDH1A1LMNAHPGDMAPTGAA
SCHEMBL7065660 0.79 ALDH1A1 (0.39) ALDH1A1LMNAMAPTGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313461-A2 THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS Melacure Therapeutics AB (SE) 2003-05-28 EP claimed
WO-2002011715-A2 THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS MELACURE THERAPEUTICS AB (SE) 2002-02-14 WO claimed
EP-1313461-A2 THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS Melacure Therapeutics AB (SE) 2003-05-28 EP disclosed
WO-2002011715-A2 THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS MELACURE THERAPEUTICS AB (SE) 2002-02-14 WO disclosed