SCHEMBL70625

SCHEMBL70625

Oc1ccc(-c2cccc(O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 10/20 1.00
HSD17B2 P37059 10/20 1.00
CYP3A4 P08684 3/20 0.90
CYP2C9 P11712 3/20 0.90
ESR1 P03372 6/20 0.80
MEN1 O00255 1/20 0.80
KMT2A Q03164 1/20 0.80
ABL1 P00519 2/20 0.74
ABCB1 P08183 2/20 0.74
BCR P11274 2/20 0.74
ESR2 Q92731 6/20 0.71
CYP1A2 P05177 1/20 0.71
CYP2D6 P10635 1/20 0.71
CYP2B6 P20813 1/20 0.71
CYP2C19 P33261 1/20 0.71
MMP3 P08254 1/20 0.62
BCL2L1 Q07817 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404406 1.00 HSD17B1 (1.00) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL1180998 1.00 HSD17B1 (1.00) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL7129229 1.00 HSD17B1 (1.00) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL1179866 0.97 HSD17B1 (0.95) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Bromide SCHEMBL30870493 0.97 HSD17B1 (0.95) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Hydrogen Sulfide SCHEMBL23879303 0.97 HSD17B1 (0.95) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL4399187 0.95 HSD17B1 (0.91) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL7898375 0.95 HSD17B1 (1.00) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Formaldehyde SCHEMBL28913385 0.93 HSD17B1 (0.86) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL8050006 0.92 HSD17B1 (0.94) HSD17B1HSD17B2CYP3A4CYP2C9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117085143-A PROTACs nano blocking agent for estrogen receptor and preparation method and application thereof 郑州大学 2023-11-21 CN claimed
US-20230111779-A1 METHODS OF MANUFACTURE OF DIANHYDRIDES CHAULAGAIN MANI RAJ (US) 2023-04-13 US claimed
EP-3888940-B1 A RUBBER COMPOSITION AND A RUBBER PRODUCT GOODYEAR TIRE & RUBBER (US) 2023-01-11 EP claimed
CN-115286753-A Styrene modified phenolic resin and preparation method thereof 南京师范大学 2022-11-04 CN claimed
CN-110818593-B Refining method of o-hydroxybenzonitrile 湖南化工研究院有限公司 2022-06-14 CN claimed
US-10964971-B2 Battery casing and battery including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-30 US claimed
CN-110818593-A Refining method of o-hydroxybenzonitrile 湖南化工研究院有限公司 2020-02-21 CN claimed
US-20190190055-A1 BATTERY CASING AND BATTERY INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-06-20 US claimed
CN-107750404-A The Organic Light Emitting Diode of different substrates compound is included in the first and second electron transfer layers 诺瓦尔德股份有限公司 2018-03-02 CN claimed
US-8952121-B2 Polymer composition and method of making the same SILECS OY (FI) 2015-02-10 US claimed
US-5102935-A With low molecular weight, liquid crystalline esters and/or ester amides BAYER AKTIENGESELLSCHAFT (DE) 1992-04-07 US claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed
EP-0254755-B1 HEAT-CURABLE ORGANOSOL AND ITS USE ICI Lacke Farben GmbH (DE) 1989-05-31 EP claimed
US-4814416-A SULFONE CONTAINING DIOLS HUELS AKTIENGESELLSCHAFT (DE) 1989-03-21 US claimed
US-4603190-A Thermotropic aromatic polyesters having high rigidity and toughness, process for the production thereof and the use thereof for the production of moulded articles, filaments, fibres and films BAYER AKTIENGESELLSCHAFT (DE) 1986-07-29 US claimed
US-4536561-A RIGID, TOUGH MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230111779-A1 METHODS OF MANUFACTURE OF DIANHYDRIDES H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NISCH, HDHD5 HSD17B1 2783/4885HSD17B2 2816/4885CYP3A4 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.