Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 3/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763380 | 0.86 | KDM5A (0.48) | KDM5AKDM4CMAP2K1KDM4ENR4A2 | |
| SCHEMBL6433898 | 0.82 | KDM4C (0.45) | KDM5AKDM4CKDM4ETET2TET1 | |
| SCHEMBL1762964 | 0.78 | CYP3A4 (0.49) | KDM4ENR4A2ALDH1A1 | |
| SCHEMBL1763902 | 0.76 | NR4A2 (0.40) | KDM5AKDM4CMAP2K1KDM4ENR4A2 | |
| SCHEMBL7064347 | 0.75 | MAP2K1 (0.48) | MAP2K1KDM4ENR4A2ALDH1A1RAB9A | |
| SCHEMBL7063086 | 0.73 | NR4A2 (0.40) | MAP2K1KDM4ENR4A2AXLALDH1A1 | |
| SCHEMBL1763185 | 0.73 | NR4A2 (0.45) | KDM5AKDM4CMAP2K1NR4A2AXL | |
| SCHEMBL27583264 | 0.71 | KDM5A (0.33) | KDM5AKDM4CMAP2K1KDM4EL3MBTL1 | |
| SCHEMBL12238753 | 0.69 | KDM5A (0.44) | KDM5AKDM4CMAP2K1NR4A2TET2 | |
| SCHEMBL12215399 | 0.69 | KDM5A (0.51) | KDM5AKDM4CMAP2K1KDM4ENR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | KDM5A 288/4885KDM4C 734/4885MAP2K1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.