Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | HAT1 | O14929 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389085 | 0.85 | MAP2K1 (0.61) | MAP2K1NR4A2CREBBPKDM4EMAPT | |
| SCHEMBL31753964 | 0.85 | MAP2K1 (0.61) | MAP2K1NR4A2CREBBPKDM4EMAPT | |
| SCHEMBL1993768 | 0.85 | CYP2C19 (0.43) | MAP2K1CYP2C19KDM4EKDRMAPT | |
| SCHEMBL6432355 | 0.81 | CYP2C19 (0.49) | MAP2K1CYP2C19KDM4EHAT1EP300 | |
| SCHEMBL3889448 | 0.80 | PARP1 (0.47) | MAP2K1CYP2C19KDM4EHAT1EP300 | |
| Potassium Ion SCHEMBL7064340 | 0.80 | CYP2C19 (0.46) | MAP2K1CYP2C19KDM4EHAT1EP300 | |
| SCHEMBL12479995 | 0.80 | PBRM1 (0.54) | MAP2K1CYP2C19NR4A2CREBBPKDM4E | |
| SCHEMBL29601281 | 0.80 | PBRM1 (0.54) | MAP2K1CYP2C19NR4A2CREBBPKDM4E | |
| SCHEMBL2816680 | 0.78 | TET2 (0.51) | CYP2C19KDM4EHAT1EP300MAPT | |
| SCHEMBL29600892 | 0.78 | TET2 (0.51) | CYP2C19KDM4EHAT1EP300MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | MAP2K1 3885/4885CYP2C19 3101/4885NR4A2 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.