Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063245 | 0.84 | MAPT (0.62) | TERTMAPTL3MBTL1EGFRMAPK1 | |
| SCHEMBL7063665 | 0.80 | MAPT (0.73) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| SCHEMBL7060111 | 0.76 | MAPT (0.65) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| SCHEMBL6660403 | 0.75 | MAPT (0.69) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| SCHEMBL713073 | 0.74 | TERT (0.74) | TERTMAPTL3MBTL1TDP1NPSR1 | |
| Trifluoroacetic Acid SCHEMBL7065193 | 0.73 | MAPT (0.58) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| SCHEMBL2463193 | 0.73 | MAPT (1.00) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7064986 | 0.72 | MAPT (0.41) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7061578 | 0.72 | DPP7 (0.52) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 | |
| SCHEMBL3273424 | 0.72 | MAPT (0.97) | MAPTL3MBTL1EGFRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130272-A1 | Anthracene derivatives as anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-07-10 | — | — | US | disclosed |
| EP-1244624-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001044190-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130272-A1 | Anthracene derivatives as anti-cancer agents | TOP2B, TOP1, TOP2A | TERT 1203/4885MAPT 4884/4885L3MBTL1 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.