Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139258 | 0.86 | LMNA (0.71) | ESR1ESR2LMNACYP3A4KMT2A | |
| SCHEMBL12793146 | 0.86 | LMNA (0.71) | ESR1ESR2LMNACYP3A4KMT2A | |
| SCHEMBL8432942 | 0.86 | LMNA (0.71) | ESR1ESR2LMNACYP3A4KMT2A | |
| SCHEMBL7517855 | 0.84 | SRD5A2 (0.74) | ESR1SRD5A2ESR2SRD5A1 | |
| SCHEMBL9235891 | 0.83 | SRD5A2 (0.76) | ESR1SRD5A2ESR2LMNACYP3A4 | |
| SCHEMBL15417788 | 0.82 | ESR1 (0.51) | ESR1SRD5A2ESR2LMNACYP3A4 | |
| SCHEMBL8011297 | 0.82 | LMNA (0.77) | ESR1LMNACYP3A4KMT2AMEN1 | |
| SCHEMBL2285480 | 0.82 | ESR1 (0.73) | ESR1ESR2LMNACYP3A4KMT2A | |
| SCHEMBL13909281 | 0.82 | ESR1 (0.73) | ESR1ESR2LMNACYP3A4KMT2A | |
| SCHEMBL21388244 | 0.82 | ESR1 (0.73) | ESR1ESR2LMNACYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039554-A1 | ENANTIOMERS OF STEROIDS FOR THE ENHANCEMENT OF MEMORY AND COGNITIVE FUNCTION | BAULIEU ETIENNE-EMILE (FR) | 2003-05-15 | — | — | WO | disclosed |