Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 12/20 | 0.39 |
| ▸ | KLK1 | P06870 | 7/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477108 | 0.92 | PTGER4 (0.39) | S1PR3 | |
| SCHEMBL7064689 | 0.80 | KLKB1 (0.41) | KLKB1KLK1S1PR3ELANE | |
| SCHEMBL6477346 | 0.80 | CES2 (0.36) | — | |
| SCHEMBL6477071 | 0.75 | PTGER4 (0.38) | S1PR3 | |
| SCHEMBL6484455 | 0.75 | PTGER4 (0.38) | S1PR3 | |
| SCHEMBL6814257 | 0.71 | NAMPT (0.39) | S1PR3ELANENAMPT | |
| SCHEMBL6477069 | 0.70 | S1PR3 (0.39) | KLKB1S1PR3 | |
| SCHEMBL6818974 | 0.70 | S1PR3 (0.35) | S1PR3 | |
| SCHEMBL6814261 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL6289363 | 0.67 | KDM4E (0.43) | S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |