Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477879 | 0.91 | KDM5A (0.33) | ALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL6814255 | 0.91 | KDM5A (0.33) | MEN1KMT2AKDM4EALDH1A1NCOA1 | |
| SCHEMBL6814257 | 0.84 | NAMPT (0.39) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6477074 | 0.70 | CES2 (0.33) | ALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL6486635 | 0.70 | P2RY14 (0.32) | ALDH1A1 | |
| SCHEMBL7063737 | 0.69 | KLKB1 (0.39) | — | |
| SCHEMBL6822205 | 0.67 | LOXL2 (0.39) | KDM5AKDM4CKDM5B | |
| SCHEMBL6484477 | 0.65 | HCAR3 (0.32) | KMT2AALDH1A1 | |
| SCHEMBL6477346 | 0.64 | CES2 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6482492 | 0.64 | DAO (0.34) | ALDH1A1KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |