Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.85 |
| ▸ | MEN1 | O00255 | 6/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410636 | 0.88 | KMT2A (0.68) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL12894525 | 0.86 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8407518 | 0.86 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8177271 | 0.83 | KMT2A (0.62) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7733701 | 0.82 | L3MBTL1 (1.00) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3832753 | 0.82 | KMT2A (0.65) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3088486 | 0.82 | MEN1 (0.60) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11661063 | 0.81 | MAPT (0.59) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31155744 | 0.81 | KMT2A (0.59) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL12869856 | 0.81 | KMT2A (0.59) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244847-B2 | Benzimidazole compounds | ISIS PHARMACEUTICALS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1049666-B1 | NOVEL NAPHTHYL-SUBSTITUTED AND ANILIDE-SUBSTITUTED SULFONAMIDES | BAYER AG (DE) | 2003-06-04 | — | — | EP | disclosed |
| US-6417181-B1 | VIRICIDES FORMED BY CATALYTIC HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
| CN-1294578-A | Novel naphthyl and anilide substituted sulfonamides | BAYER AG (DE) | 2001-05-09 | — | — | CN | disclosed |
| WO-2001007403-A1 | NAPHTHYL-SUBSTITUTED SULFONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | disclosed |
| EP-1049667-A1 | NOVEL NAPHTHYL SUBSTITUTED AND HETEROCYCLIC SUBSTITUTED SULFONAMIDES | BAYER AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-1049666-A1 | NOVEL NAPHTHYL-SUBSTITUTED AND ANILIDE-SUBSTITUTED SULFONAMIDES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037609-A1 | NOVEL NAPHTHYL-SUBSTITUTED AND ANILIDE-SUBSTITUTED SULFONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |
| WO-1999037608-A1 | NOVEL NAPHTHYL SUBSTITUTED AND HETEROCYCLIC SUBSTITUTED SULFONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |