Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063751 | 0.83 | KMT2A (0.85) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL8410636 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL8407518 | 0.81 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL12894525 | 0.81 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL3832753 | 0.80 | KMT2A (0.65) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11661063 | 0.79 | MAPT (0.59) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL10420551 | 0.78 | KMT2A (0.61) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL8462705 | 0.77 | MEN1 (0.65) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7956933 | 0.77 | MAPT (0.52) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL8321463 | 0.76 | PDK1 (0.61) | KMT2AMEN1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000068186-A1 | BIS-SULFONAMIDE WITH ANTI-HCMV EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |