Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469093 | 0.86 | ALDH1A1 (0.44) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL4363348 | 0.86 | GPR35 (0.60) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL4582714 | 0.85 | GPR35 (0.47) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL594277 | 0.82 | GPR35 (0.44) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL1670128 | 0.82 | GPR35 (0.44) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL23229249 | 0.82 | PTGER4 (0.48) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL27677603 | 0.82 | ALDH1A1 (0.41) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL1162131 | 0.81 | GPR35 (0.62) | GPR35ESR1ESR2TSHRALDH1A1 | |
| SCHEMBL2956655 | 0.79 | GPR35 (0.42) | GPR35ESR1ESR2CA12CA1 | |
| SCHEMBL26654588 | 0.79 | GRIN2D (0.44) | GPR35ESR1ESR2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314036-A2 | BIOSENSOR ASSAY DEVICE AND METHOD | Helix Biopharma Corp. (CA) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018952-A2 | BIOSENSOR ASSAY DEVICE AND METHOD | HELIX BIOPHARMA CORPORATION (CA) | 2002-03-07 | — | — | WO | disclosed |