Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24772918 | 0.97 | TSHR (0.60) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL24774025 | 0.97 | TSHR (0.60) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL7065615 | 0.95 | TSHR (0.57) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| Tetrahydrofuran SCHEMBL3265313 | 0.92 | TSHR (0.68) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL30988915 | 0.90 | TSHR (0.57) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| Dioxane SCHEMBL1449342 | 0.89 | TSHR (0.72) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL7062871 | 0.87 | TSHR (0.62) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL30387832 | 0.87 | TSHR (0.55) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL4850089 | 0.87 | TSHR (0.55) | TSHRCYP2A6HTR2CDRD2DRD1 | |
| SCHEMBL2062312 | 0.82 | TSHR (0.53) | TSHRCYP2A6HTR2CDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901787-B1 | Stabilized pharmaceutical composition | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0952826-B1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6187340-B1 | TABLETS WITH COATINGS THAT PROTECT FROM LIGHT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0952826-A1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | Takeda Chemical Industries, Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5962535-A | SYNERGISTIC MIXTURE OF IDEBENONE AND ACETYLCHOLINESTERASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0901787-A1 | Stabilized pharmaceutical composition | Takeda Chemical Industries, Ltd. (JP) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998031356-A1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-23 | — | — | WO | disclosed |
| EP-0487071-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5273974-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0487071-A1 | Condensed heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |