Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL3265313 | 0.92 | TSHR (0.68) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL24772918 | 0.92 | TSHR (0.60) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL24774025 | 0.92 | TSHR (0.60) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL7063876 | 0.89 | TSHR (0.63) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| Dioxane SCHEMBL31229845 | 0.88 | TSHR (0.53) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL7062871 | 0.87 | TSHR (0.62) | TSHRLMNACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8355 | 0.85 | TSHR (1.00) | TSHRHTR2CHPGDL3MBTL1MAOB | |
| SCHEMBL385555 | 0.85 | TSHR (1.00) | TSHRHTR2CHPGDL3MBTL1MAOB | |
| SCHEMBL11606739 | 0.85 | TSHR (1.00) | TSHRHTR2CHPGDL3MBTL1MAOB | |
| SCHEMBL11645158 | 0.85 | TSHR (1.00) | TSHRHTR2CHPGDL3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091134-A | POLYPROPYLENE OR PROPYLENE-ETHYLENE COPOLYMER, RUBBER, TACKIFIER, ASPHALT | UEMURA MASARU | 1978-05-23 | — | — | US | claimed |
| US-3967020-A | ETHYLENE-VINYL ACETATE COPOLYMER, COPOLYMERS OF ETHYLENE-PROPYLENE AND BUTADIENE-STYRENE, ASPHALT | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1976-06-29 | — | — | US | claimed |
| US-7910018-B2 | Compounds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-20090066905-A1 | Componds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2009-03-12 | — | — | US | disclosed |
| EP-1814870-A2 | BENZO-1,3-DIOXANES FOR USE IN LIQUID CRYSTAL DEVICES | Qinetiq Limited (GB) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006048620-A2 | BENZO-1, 3-DIOXANES FOR USE IN LIQUID CRYSTAL DEVICES | QINETIQ LIMITED (GB) | 2006-05-11 | — | — | WO | disclosed |
| US-4091134-A | POLYPROPYLENE OR PROPYLENE-ETHYLENE COPOLYMER, RUBBER, TACKIFIER, ASPHALT | UEMURA MASARU | 1978-05-23 | — | — | US | disclosed |
| US-3967020-A | ETHYLENE-VINYL ACETATE COPOLYMER, COPOLYMERS OF ETHYLENE-PROPYLENE AND BUTADIENE-STYRENE, ASPHALT | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066905-A1 | Componds for use in liquid crystal devices | FZD7, CFD, PYCARD | TSHR 4686/4885LMNA 1092/4885CRHBP 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.