Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.47 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.42 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351360 | 0.89 | METAP2 (0.55) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 | |
| SCHEMBL6347687 | 0.88 | METAP2 (0.50) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 | |
| SCHEMBL6353746 | 0.87 | SIRT2 (0.61) | SIRT2AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6833917 | 0.85 | MAPK1 (0.50) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 | |
| SCHEMBL6349554 | 0.84 | AKR1C2 (0.48) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 | |
| SCHEMBL6356961 | 0.84 | METAP2 (0.53) | METAP2SIRT2SLC10A6KDM4EMAPK1 | |
| SCHEMBL6349263 | 0.84 | DNMT3A (0.48) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 | |
| SCHEMBL6350888 | 0.83 | METAP2 (0.52) | METAP2SIRT2SLC10A6HTTSLC10A2 | |
| SCHEMBL6349003 | 0.83 | SIRT2 (0.49) | SIRT2AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6349380 | 0.82 | RPA1 (0.51) | METAP2SIRT2SLC10A6AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |