Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | MMP8 | P22894 | 6/20 | 0.43 |
| ▸ | MMP13 | P45452 | 6/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826913 | 0.87 | DPP4 (0.48) | HRH2HRH1CPB2DPP4MMP1 | |
| Hydrochloric Acid SCHEMBL5891461 | 0.82 | HRH2 (0.44) | HRH2HRH1DPP4MMP1MMP2 | |
| SCHEMBL7352932 | 0.81 | METAP2 (0.47) | CPB2DPP4MMP1MMP2MMP3 | |
| SCHEMBL7558136 | 0.81 | METAP2 (0.47) | CPB2DPP4MMP1MMP2MMP3 | |
| SCHEMBL15764244 | 0.81 | MMP1 (0.44) | HRH2HRH1DPP4MMP1MMP2 | |
| SCHEMBL7357465 | 0.81 | METAP2 (0.47) | CPB2DPP4MMP1MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL5891522 | 0.79 | HRH2 (0.44) | HRH2HRH1DPP4 | |
| SCHEMBL16310391 | 0.79 | MMP1 (0.48) | CPB2MMP1MMP2MMP3MMP8 | |
| SCHEMBL6823772 | 0.79 | DPP4 (0.39) | HRH2HRH1CPB2DPP4SMN1; SMN2 | |
| SCHEMBL8360504 | 0.78 | DPP7 (0.50) | CPB2DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |