SCHEMBL706437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10784715	0.88	TDP1 (0.58)	HPSEF10TDP1MEN1TTR
	SCHEMBL28090366	0.84	TDP1 (0.55)	HPSEF10TDP1MEN1TTR
	SCHEMBL30127752	0.80	TDP1 (0.53)	TDP1MEN1TTRKMT2AATM
	SCHEMBL16792668	0.80	TDP1 (0.53)	TDP1MEN1TTRKMT2AATM
	SCHEMBL3900288	0.80	TDP1 (0.56)	HPSEF10TDP1MEN1TTR
	SCHEMBL3840523	0.78	HPSE (0.56)	HPSETDP1KMT2AHSPB1MAPT
	SCHEMBL3888921	0.78	TDP1 (0.60)	HPSETDP1MEN1TTRPPOX
	SCHEMBL28536955	0.78	PYGL (0.50)	F10TDP1PYGLHTTTSHR
	SCHEMBL17786752	0.78	ATM (0.62)	TDP1MEN1KMT2AATMHSPB1
	SCHEMBL4452102	0.77	KMT2A (0.55)	HPSETDP1MEN1KMT2APYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.