Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470522 | 0.99 | LMNA (0.39) | EP300MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1224879 | 0.85 | EP300 (0.46) | EP300ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL12883796 | 0.85 | EP300 (0.36) | EP300 | |
| SCHEMBL12883799 | 0.83 | EP300 (0.39) | EP300MAPTALDH1A1RAB9AGAA | |
| SCHEMBL7062249 | 0.76 | ALB (0.35) | EP300NPC1 | |
| SCHEMBL12883815 | 0.76 | LMNA (0.35) | MAPTALDH1A1RAB9ALMNAKDM4E | |
| SCHEMBL1224033 | 0.76 | ASAH1 (0.57) | LMNAASAH1CYP3A4CYP2D6MAPK3 | |
| SCHEMBL12883801 | 0.75 | ALB (0.34) | EP300 | |
| SCHEMBL3823927 | 0.74 | SMN1; SMN2 (0.62) | LMNAGAAASAH1CYP3A4CYP2D6 | |
| SCHEMBL2221563 | 0.74 | ALB (0.39) | EP300ALDH1A1LMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311524-A2 | 5'-DEOXY-N-(SUBSTITUTED OXYCARBONYL)-5-FLUOROCYTOSINE AND DERIVATIVES THEREOF, METHOD OF PREPARING SAME, AND ANTICANCER COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENTS | Kolon Industries, Inc. (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002011668-A2 | 5'-DEOXY-N-(SUBSTITUTED OXYCARBONYL)-5-FLUOROCYTOSINE AND DERIVATIVES THEREOF, METHOD OF PREPARING SAME, AND ANTICANCER COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENTS | KOLON INDUSTRIES, INC. (KR) | 2002-02-14 | — | — | WO | disclosed |