SCHEMBL7064682

SCHEMBL7064682

CCCc1cccc(CC(C)C)c1O

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.77
GABRB2 P47870 3/20 0.77
ELANE P08246 4/20 0.42
CTSG P08311 2/20 0.42
IAPP P10997 4/20 0.41
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
PRKCI P41743 1/20 0.40
CDK1 P06493 1/20 0.35
CDK2 P24941 1/20 0.35
DAO P14920 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864085 0.88 GABRA1 (1.00) GABRA1GABRB2ELANECTSGCDK1
SCHEMBL10595735 0.86 GABRA1 (0.67) GABRA1GABRB2ELANECTSGALOX5
SCHEMBL674691 0.85 GABRA1 (0.64) GABRA1GABRB2ELANECTSGIAPP
SCHEMBL7064652 0.84 GABRA1 (0.83) GABRA1GABRB2ELANECTSGIAPP
SCHEMBL31376379 0.83 GABRA1 (0.61) GABRA1GABRB2ELANECTSGIAPP
SCHEMBL23964428 0.81 GABRA1 (0.65) GABRA1GABRB2ELANECTSG
SCHEMBL14551465 0.80 GABRA1 (0.83) GABRA1GABRB2ELANECTSGCDK1
SCHEMBL1005366 0.79 GABRA1 (0.77) GABRA1GABRB2ELANECTSGIAPP
SCHEMBL9351914 0.79 ALOX5 (0.47) GABRA1GABRB2ELANECTSGALOX5
SCHEMBL6870041 0.78 TSHR (0.53) GABRA1GABRB2ELANECTSGIAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101595096-A Substituted carbinol compounds KOWA CO (JP) 2009-12-02 CN disclosed
EP-0995737-B1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols HONSHU CHEMICAL IND (JP) 2003-06-04 EP disclosed
US-6284931-B1 REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-09-04 US disclosed
EP-0995737-A1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols Honshu Chemical Industry Co. Ltd. (JP) 2000-04-26 EP disclosed