SCHEMBL7064844

SCHEMBL7064844

CC(C)Cc1cccc(C(C)C)c1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.73
GABRB2 P47870 5/20 0.73
GABRG2 P18507 2/20 0.61
GABRB3 P28472 2/20 0.61
TSHR P16473 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP3A4 P08684 2/20 0.61
FAAH O00519 1/20 0.61
LMNA P02545 1/20 0.61
HPGD P15428 1/20 0.61
GABRB1 P18505 1/20 0.61
PTGS1 P23219 1/20 0.61
SLC6A2 P23975 1/20 0.61
HTR2C P28335 1/20 0.61
GABRA5 P31644 1/20 0.61
GABRA3 P34903 1/20 0.61
HTR2B P41595 1/20 0.61
GABRA2 P47869 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864085 0.85 GABRA1 (1.00) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL13405958 0.85 GABRA1 (0.57) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL21734367 0.83 GABRA1 (0.67) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL4318572 0.83 GABRA1 (0.55) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL4459158 0.82 GABRA1 (0.64) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL2927393 0.82 GABRA1 (0.64) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL4310555 0.81 GABRA1 (0.57) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL19478609 0.80 GABRA1 (0.52) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL14995226 0.79 GABRA1 (0.79) GABRA1GABRB2GABRG2GABRB3TSHR
SCHEMBL1053654 0.79 GABRA1 (0.79) GABRA1GABRB2TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995737-B1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols HONSHU CHEMICAL IND (JP) 2003-06-04 EP disclosed
US-6284931-B1 REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-09-04 US disclosed
EP-0995737-A1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols Honshu Chemical Industry Co. Ltd. (JP) 2000-04-26 EP disclosed