Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920328 | 0.88 | GABRA1 (0.64) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL21734367 | 0.85 | GABRA1 (0.67) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL10486191 | 0.84 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL31028132 | 0.84 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL9204057 | 0.84 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL7066182 | 0.84 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL8409222 | 0.83 | GABRA1 (0.53) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL2927393 | 0.83 | GABRA1 (0.64) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL9162954 | 0.83 | GABRA1 (0.64) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL15253134 | 0.83 | GABRA1 (0.64) | GABRA1GABRB2GABRG2GABRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273256-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| WO-2015157057-A1 | MACROCYCLES | LUMIPHORE, INC (US) | 2015-10-15 | — | — | WO | disclosed |
| CN-104788303-A | Method for synthesizing biphenyl diquinone derivative under catalysis of supported semiconductor | NANJING UNIVERSITY OF TECHNOLOGY | 2015-07-22 | — | — | CN | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| EP-2520290-A1 | Propofol analogs, process for their preparation, and methods of use | Abraxis BioScience, LLC (US) | 2012-11-07 | — | — | EP | disclosed |
| US-7576094-B2 | Spiro derivatives as lipoxygenase inhibitors | ELI LILLY AND COMPANY (US) | 2009-08-18 | — | — | US | disclosed |
| CN-101115734-A | Spiro derivatives as lipoxygenase inhibitors | LILLY CO ELI (US) | 2008-01-30 | — | — | CN | disclosed |
| EP-1836183-A2 | SPIRO DERIVATIVES AS LIPOXYGENASE INHIBITORS | Galileo Pharmaceuticals, Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006065686-A2 | SPIRO DERIVATIVES AS LIPOXYGENASE INHIBITORS | GALILEO PHARMACEUTICALS, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20060128790-A1 | Spiro derivatives as lipoxygenase inhibitors | GALILEO PHARMACEUTICALS, INC. | 2006-06-15 | — | — | US | disclosed |
| EP-0995737-B1 | Process for producing 3,3,5-trimethylcyclohexylidenebisphenols | HONSHU CHEMICAL IND (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6284931-B1 | REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| EP-0995737-A1 | Process for producing 3,3,5-trimethylcyclohexylidenebisphenols | Honshu Chemical Industry Co. Ltd. (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5096949-A | Heat and oxidation resistance, photostability; polyolefins; uv rad | THE B. F. GOODRICH COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4920228-A | N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith | THE B. F. GOODRICH COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| US-4780495-A | HEAT, OXIDATION, AND LIGHT STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| US-4692555-A | Preparation of diphenolics | ETHYL CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273256-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | GABRA1 3299/4885GABRB2 2904/4885GABRG2 3930/4885 |
| US-20060128790-A1 | Spiro derivatives as lipoxygenase inhibitors | ALOX15B, ALOX5, ALOX15 | GABRA1 3804/4885GABRB2 3651/4885GABRG2 4275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.