Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496007 | 0.81 | OPRM1 (0.83) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL7070238 | 0.81 | OPRM1 (0.65) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6504138 | 0.81 | CHRM1 (0.77) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6507890 | 0.79 | CYP3A4 (0.49) | OPRM1OPRL1DRD2DRD4 | |
| SCHEMBL6505610 | 0.79 | OPRM1 (0.68) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6507099 | 0.78 | OPRM1 (0.65) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL7063356 | 0.76 | OPRM1 (0.59) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6504966 | 0.76 | OPRM1 (0.70) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6497550 | 0.74 | OPRM1 (0.67) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL6504972 | 0.73 | OPRM1 (0.68) | OPRM1OPRK1OPRL1CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |