SCHEMBL7064946

SCHEMBL7064946

Cl[Ti](Cl)(C1C(c2ccc3ccccc3n2)=Cc2ccccc21)C1C(c2ccc3ccccc3n2)=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 12/20 0.37
NPC1 O15118 11/20 0.37
CYP3A4 P08684 4/20 0.37
AR P10275 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
KDM4E B2RXH2 8/20 0.36
SMN1; SMN2 Q16637 7/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 9/20 0.36
HSD17B10 Q99714 4/20 0.36
PKM P14618 4/20 0.36
HPGD P15428 4/20 0.36
TP53 P04637 4/20 0.36
MAPT P10636 4/20 0.36
PMP22 Q01453 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062192 0.77 RAB9A (0.38) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL7065272 0.77 RAB9A (0.39) RAB9ANPC1CYP3A4ARCYP1A2
Hydrochloric Acid SCHEMBL7065269 0.77 RAB9A (0.42) RAB9ANPC1CYP3A4ARCYP1A2
Hydrochloric Acid SCHEMBL7064943 0.75 RAB9A (0.41) RAB9ANPC1CYP3A4ARCYP1A2
Hydrochloric Acid SCHEMBL7062188 0.75 RAB9A (0.41) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL7061668 0.75 KDM4E (0.39) RAB9ANPC1CYP1A2KDM4ESMN1; SMN2
SCHEMBL394240 0.72
SCHEMBL394873 0.68 L3MBTL1 (0.30) MEN1KMT2AKDM4ETDP1ALDH1A1
SCHEMBL7062676 0.68 RAB9A (0.41) RAB9ANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL7060541 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635733-B2 Coordination catalyst; radiation transparent, elasticity CHISSO CORPORATION (JP) 2003-10-21 US disclosed
US-6479646-B1 Metallocene compounds having indenyl ligand and catalysts for olefin polymerization containing the same CHISSO CORPORATION (JP) 2002-11-12 US disclosed
US-20020002261-A1 Elastomeric polypropylene JNC PETROCHEMICAL CORPORATION (JP) 2002-01-03 US disclosed
US-20010031834-A1 Using coordination catalyst; flexibility, elasticity; molding materials CHISSO CORPORATION 2001-10-18 US disclosed