Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.48 |
| ▸ | THRA | P10827 | 14/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041277 | 0.81 | THRA (0.73) | THRBTHRA | |
| SCHEMBL5041149 | 0.81 | THRA (0.56) | THRBTHRA | |
| SCHEMBL5042712 | 0.79 | THRA (0.55) | THRBTHRA | |
| SCHEMBL5045261 | 0.79 | THRA (0.52) | THRBTHRA | |
| SCHEMBL5042151 | 0.78 | THRA (0.51) | THRBTHRA | |
| SCHEMBL5045356 | 0.78 | THRA (0.50) | THRBTHRA | |
| SCHEMBL5561304 | 0.76 | THRB (0.39) | THRBTHRA | |
| SCHEMBL5041151 | 0.73 | THRB (0.64) | THRBTHRA | |
| SCHEMBL14264302 | 0.73 | THRA (0.53) | THRBTHRA | |
| SCHEMBL14264298 | 0.72 | THRA (0.55) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039456-A2 | PROCESS FOR THE PREPARATION OF ANILINE-DERIVED THYROID RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-05-15 | — | — | WO | claimed |