Lithium

Lithium

SCHEMBL7065112

COC(=O)c1oc(C(=O)OC)c(O)c1O.[Li].[Li]

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CELA1 Q9UNI1 1/20 0.44
KDM4E B2RXH2 4/20 0.41
LMNA P02545 3/20 0.41
XDH P47989 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
NFKB1 P19838 1/20 0.41
GFER P55789 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
FUT7 Q11130 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 6/20 0.40
NPSR1 Q6W5P4 1/20 0.39
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA7 P43166 4/20 0.38
CA9 Q16790 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453281 0.97 CELA1 (0.46) CELA1KDM4ELMNAXDHPOLB
Potassium SCHEMBL7063557 0.95 CELA1 (0.44) CELA1KDM4ELMNAXDHPOLB
SCHEMBL7063431 0.95 CELA1 (0.44) CELA1KDM4ELMNAXDHPOLB
SCHEMBL8596046 0.84 ALDH1A1 (0.45) CELA1KDM4ELMNAXDHPOLB
SCHEMBL11453563 0.75 ALDH1A1 (0.40) CELA1KDM4ELMNAPOLBALDH1A1
SCHEMBL27985259 0.74 CELA1 (0.38) CELA1KDM4ELMNAXDHPOLB
SCHEMBL9825659 0.73 PTGS1 (0.48) KDM4ELMNAGAAL3MBTL1ALDH1A1
Potassium Ion SCHEMBL7063553 0.73 CELA1 (0.43) CELA1KDM4ELMNAALDH1A1NPSR1
Lithium Ion SCHEMBL7065110 0.73 CELA1 (0.43) CELA1KDM4ELMNAALDH1A1NPSR1
SCHEMBL7063428 0.73 CELA1 (0.43) CELA1KDM4ELMNAALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6608164-B2 Diaryl carbonate reacted with dihydroxy aromatic compounds in the presence of a transesterification catalyst; furan diol derivative is dimethyl 3,4-dihydroxy-2,5-furandiacarboxylate disodium salt GENERAL ELECTRIC COMPANY 2003-08-19 US disclosed
US-20030114633-A1 Salts of heterocyclic diols as catalysts for melt polycarbonate GENERAL ELECTRIC COMPANY 2003-06-19 US disclosed