Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453281 | 0.86 | CELA1 (0.46) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| Potassium SCHEMBL7063557 | 0.84 | CELA1 (0.44) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| SCHEMBL7063431 | 0.84 | CELA1 (0.44) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| Lithium SCHEMBL7065112 | 0.84 | CELA1 (0.44) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| SCHEMBL8598477 | 0.79 | MAPT (0.45) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL14129723 | 0.71 | ALDH1A1 (0.52) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| SCHEMBL1714747 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| SCHEMBL27985259 | 0.69 | CELA1 (0.38) | ALDH1A1CELA1KDM4ELMNATDP1 | |
| SCHEMBL9825659 | 0.69 | PTGS1 (0.48) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL14129737 | 0.68 | ALDH1A1 (0.48) | ALDH1A1CELA1KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532120-B1 | Process for the preparation of 4-hydroxy-3(2H)furanones | TASTEMAKER BV (NL) | 1998-01-07 | — | — | EP | disclosed |
| US-5412121-A | Process for the preparation of 4-hydroxy-3[2H]furanones | TASTEMAKER (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0532120-A1 | Process for the preparation of 4-hydroxy-3(2H)furanones | Tastemaker B.V. (NL) | 1993-03-17 | — | — | EP | disclosed |