Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.34 |
| ▸ | KLK7 | P49862 | 2/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662051 | 1.00 | ADORA2B (0.37) | ADORA2BALDH1A1POLBKDM4EHPGD | |
| SCHEMBL3784269 | 0.85 | ELANE (0.43) | KLK7KLK5GPR119 | |
| SCHEMBL28379112 | 0.85 | ELANE (0.43) | KLK7KLK5GPR119 | |
| SCHEMBL9286553 | 0.85 | ELANE (0.43) | KLK7KLK5GPR119 | |
| SCHEMBL6860067 | 0.80 | ADORA2B (0.39) | ADORA2BALDH1A1POLBKDM4EHPGD | |
| SCHEMBL6860058 | 0.80 | ADORA2B (0.39) | ADORA2BALDH1A1POLBKDM4EHPGD | |
| SCHEMBL6860063 | 0.80 | ADORA2B (0.39) | ADORA2BALDH1A1POLBKDM4EHPGD | |
| SCHEMBL5963831 | 0.74 | KLK7 (0.33) | KLK7KLK5 | |
| SCHEMBL7729786 | 0.74 | ELANE (0.47) | ALDH1A1POLBKDM4EHPGDGAA | |
| SCHEMBL8593171 | 0.73 | ADORA2B (0.45) | ADORA2BALDH1A1POLBKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083497-A1 | Taxoids, their preparation and pharmaceutical compositions containing them | AVENTIS PHARMA, S.A. | 2003-05-01 | — | — | US | disclosed |
| US-6384071-B2 | ANTITUMOR AGENTS | AVENTIS PHARMA, S.A. (FR) | 2002-05-07 | — | — | US | disclosed |
| US-20010021783-A1 | New taxoids, their preparation and pharmaceutical compositions containing them | Rhône-Poulenc Rorer S.A. | 2001-09-13 | — | — | US | disclosed |
| US-6194582-B1 | MULTI-DRUG RESISTANCE | RHONE-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |
| US-5814658-A | Taxoids, their preparation and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1998-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083497-A1 | Taxoids, their preparation and pharmaceutical compositions containing them | TBXA2R, CBR1, CBR3 | ADORA2B 1044/4885ALDH1A1 665/4885POLB 1184/4885 |
| US-20010021783-A1 | New taxoids, their preparation and pharmaceutical compositions containing them | CBR1, TBXA2R, CBR3 | ADORA2B 929/4885ALDH1A1 640/4885POLB 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.