Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065509 | 1.00 | FPR2 (0.46) | FPR2FPR1F10USP30ROCK2 | |
| SCHEMBL7064874 | 0.98 | FPR2 (0.48) | FPR2FPR1F10USP30ROCK2 | |
| SCHEMBL7062039 | 0.85 | F10 (0.49) | FPR2FPR1F10 | |
| SCHEMBL7091109 | 0.84 | FPR2 (0.47) | FPR2FPR1F10USP30HCRTR1 | |
| SCHEMBL7065471 | 0.82 | FPR2 (0.48) | FPR2FPR1F10ROCK2GPR119 | |
| SCHEMBL7064681 | 0.82 | PRSS1 (0.50) | FPR2FPR1F10 | |
| SCHEMBL7065095 | 0.82 | FPR2 (0.48) | FPR2FPR1F10ROCK2HCRTR1 | |
| SCHEMBL7065090 | 0.78 | FPR2 (0.49) | FPR2FPR1F10GPR119ALOX5AP | |
| SCHEMBL7143506 | 0.77 | USP30 (0.44) | FPR2FPR1F10USP30GPR119 | |
| SCHEMBL6163283 | 0.77 | SCN3A (0.44) | FPR2FPR1F10USP30LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | MERCK PATENT GMBH (DE) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | F5, F11, F2 | FPR2 27/4885FPR1 10/4885F10 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.