Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6436929 | 0.75 | PLG (0.48) | PLAU | |
| SCHEMBL7378240 | 0.71 | CA1 (0.42) | CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL7366869 | 0.71 | PLAU (0.41) | PLAU | |
| SCHEMBL5495888 | 0.68 | KMO (0.65) | KMOERN1CSNK2A2CSNK2BMKNK1 | |
| SCHEMBL6434174 | 0.68 | PLAU (0.50) | PLAU | |
| SCHEMBL29725579 | 0.67 | KMO (0.74) | KMOERN1MAP4K4MKNK1MKNK2 | |
| SCHEMBL29911642 | 0.67 | KMO (0.74) | KMOERN1MAP4K4MKNK1MKNK2 | |
| SCHEMBL7113226 | 0.67 | PRSS1 (0.75) | KMORXRARXRB | |
| SCHEMBL14743086 | 0.66 | KMO (0.68) | KMOERN1RXRARXRB | |
| SCHEMBL29923455 | 0.66 | KMO (0.68) | KMOERN1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030099693-A1 | Wafer | PFIZER INC. | 2003-05-29 | — | — | US | claimed |
| WO-2003037395-A1 | WAFER FOR WOUNDS | PFIZER LIMITED (GB) | 2003-05-08 | — | — | WO | claimed |
| US-20030099693-A1 | Wafer | PFIZER INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003037395-A1 | WAFER FOR WOUNDS | PFIZER LIMITED (GB) | 2003-05-08 | — | — | WO | disclosed |